It is administered every three to four weeks when used for the treatment of osteolytic bone lesions of multiple myeloma. Zoledronic acid is an injection that only requires administration every year for the treatment of osteoporosis, and every two years for the prevention of osteoporosis.Reclast may also be used to increase bone mineral density in men and to treat Paget's disease of the bone in men and women. The Reclast brand of zoledronic acid may be used to treat or prevent osteoporosis caused by menopause, steroid use, or low hormone levels due to gonadal failure.The use of zoledronic acid in non-tumor-related hypercalcemic conditions (such as hyperparathyroidism) has not been established.Zoledronic acid (including the Zometa brand) may be used to treat patients with multiple myeloma or bone metastases from solid tumors in addition to standard chemotherapy regimens.Zoledronic acid is used for the treatment of high calcium levels (hypercalcemia) associated with cancer.Zoledronic acid belongs to the class of medicines known as bisphosphonates.It also inhibits increased osteoclastic activity and the release of calcium by the skeleton induced by tumors. Zoledronic acid works by inhibiting osteoclasts which are responsible for breaking down and reabsorbing bone (by a process known as bone resorption).Zoledronic acid strengthens bones and may be used for the treatment or prevention of osteoporosis.Medically reviewed by Carmen Pope, BPharm. Zoledronic acid: 7 things you should know

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